Understanding Your Ulcerative Colitis Medications: A Comprehensive Guide

Introduction

Managing ulcerative colitis (UC) requires a comprehensive medication plan tailored to your specific needs. This guide explores the main categories of UC medications.

Medication Categories

1. Aminosalicylates (5-ASAs)

• Common names: Mesalamine, sulfasalazine, balsalazide
• Purpose: Reduce inflammation in mild to moderate UC
• Administration: Oral tablets, suppositories, or enemas

2. Corticosteroids

• Common names: Prednisone, budesonide
• Purpose: Rapid inflammation control during flares
• Duration: Short-term use only
• Note: Not for long-term maintenance

3. Immunomodulators

• Common names: Azathioprine, 6-MP, methotrexate
• Purpose: Suppress immune system response
• Timeline: May take 2-3 months for full effect

4. Biologics

• Types:
  • TNF inhibitors (adalimumab, infliximab)
  • Integrin inhibitors (vedolizumab)
  • IL-12/23 inhibitors (ustekinumab)
• Administration: Injection or infusion

Important Considerations

Medication Adherence

• Take medications as prescribed
• Don't skip doses
• Report side effects promptly

Monitoring

• Regular blood tests required
• Scheduled follow-up appointments
• Vaccination updates

Lifestyle Factors

• Maintain healthy diet
• Stay hydrated
• Track symptoms
• Avoid triggers

When to Contact Your Doctor

• Severe side effects
• Worsening symptoms
• New symptoms
• Questions about medications