Understanding Your Osteoporosis Medications: A Patient's Guide

A comprehensive overview of treatment options and proper medication use

Endocrinology

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Last updated: Mar 24, 2025

Introduction

Osteoporosis medications play a crucial role in maintaining bone health and preventing fractures. This guide will help you understand your treatment options.

Types of Medications

1. Bisphosphonates

  • Oral medications:
    • Alendronate (Fosamax®)
    • Risedronate (Actonel®)
    • Ibandronate (Boniva®)
  • Injectable medications:
    • Zoledronic acid (Reclast®)

2. Biologics

  • Denosumab (Prolia®)
    • Administered every 6 months
    • Works by blocking bone breakdown

3. Anabolic Agents

  • Teriparatide (Forteo®)
  • Abaloparatide (Tymlos®)
  • Romosozumab (Evenity®)

Proper Administration

For Oral Bisphosphonates

  1. Take first thing in the morning
  2. Take with plain water only
  3. Remain upright for 30-60 minutes
  4. Wait before eating or taking other medications

For Injectable Medications

  • Administered by healthcare professionals or self-injection
  • Follow specific schedule provided

Side Effects and Monitoring

Common Side Effects

  • Stomach upset
  • Bone/joint pain
  • Headache

Rare but Serious Side Effects

  • Osteonecrosis of the jaw
  • Atypical femur fractures

Treatment Duration

  • Varies by medication type
  • Regular evaluation of benefits vs. risks
  • Drug holidays may be recommended

Additional Measures

  • Calcium supplementation
  • Vitamin D intake
  • Regular exercise
  • Fall prevention

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