Understanding Your Medications for Substance Use Disorder

A Comprehensive Guide to Medication-Assisted Treatment (MAT)

Psychiatry

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Last updated: Mar 24, 2025

Introduction

Medication-assisted treatment (MAT) is a proven approach for managing substance use disorders. This guide will help you understand your medication options and their proper use.

Common Medications

For Opioid Use Disorder

  • Buprenorphine (Suboxone®)

    • Reduces cravings and withdrawal symptoms
    • Available as sublingual film or tablet
    • Take as prescribed, usually once daily
  • Methadone

    • Long-acting opioid agonist
    • Administered at certified clinics
    • Daily dosing initially required
  • Naltrexone (Vivitrol®)

    • Blocks opioid effects
    • Monthly injection
    • Requires complete detox first

For Alcohol Use Disorder

  • Acamprosate (Campral®)

    • Reduces cravings and withdrawal
    • Taken three times daily
    • Best started after detox
  • Naltrexone

    • Reduces alcohol cravings
    • Available as daily pill or monthly injection

Important Safety Information

  1. Never skip or adjust doses without medical supervision
  2. Keep all follow-up appointments
  3. Report side effects promptly
  4. Store medications securely
  5. Continue counseling as recommended

Success Tips

  • Set medication reminders
  • Keep emergency contacts handy
  • Attend support groups
  • Maintain healthy lifestyle habits
  • Stay connected with your healthcare team

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