Understanding Vaginal Cancer

A Comprehensive Guide for Patients

Oncology

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Last updated: Mar 24, 2025

What is Vaginal Cancer?

Vaginal cancer is a rare malignancy that develops in the vaginal tissues. It occurs when abnormal cells in the vagina grow uncontrollably, forming a tumor.

Types of Vaginal Cancer

  • Squamous Cell Carcinoma (85-90% of cases)
  • Adenocarcinoma (5-10% of cases)
  • Melanoma (rare)
  • Sarcoma (rare)

Risk Factors

  • Age over 60
  • HPV (Human Papillomavirus) infection
  • History of cervical cancer or precancerous conditions
  • Previous radiation therapy to the pelvis
  • Smoking
  • DES exposure before birth

Signs and Symptoms

Common Symptoms Include:

  • Abnormal vaginal bleeding
  • Watery vaginal discharge
  • Pelvic pain
  • Pain during intercourse
  • Difficulty or pain when urinating
  • Constipation
  • Pelvic mass

Diagnosis

  1. Physical Examination
  2. Colposcopy
  3. Biopsy
  4. Imaging Tests:
    • CT scan
    • MRI
    • PET scan

Treatment Options

Surgery

  • Local excision
  • Vaginectomy
  • Hysterectomy when necessary

Radiation Therapy

  • External beam radiation
  • Brachytherapy

Chemotherapy

  • Often combined with radiation
  • May be used for advanced cases

Prevention

  • HPV vaccination
  • Regular gynecological check-ups
  • Safe sex practices
  • Smoking cessation

Prognosis

Prognosis depends on:

  • Stage at diagnosis
  • Type of cancer
  • Overall health
  • Response to treatment

Follow-up Care

  • Regular check-ups
  • Monitoring for recurrence
  • Managing side effects
  • Emotional support

When to Contact Your Doctor

Seek immediate medical attention if you experience:

  • Unusual vaginal bleeding
  • Persistent pelvic pain
  • New or worsening symptoms

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