Understanding Ulcerative Colitis: A Comprehensive Overview

Essential Information for Patients with UC

Gastroenterology

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Last updated: Mar 24, 2025

What is Ulcerative Colitis?

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the large intestine (colon) and rectum. The condition causes inflammation and ulcers in the digestive tract's innermost lining.

Key Symptoms

  • Diarrhea, often with blood or pus
  • Abdominal pain and cramping
  • Rectal pain and bleeding
  • Urgency to defecate
  • Weight loss
  • Fatigue
  • Fever

Disease Characteristics

  • Pattern: Symptoms typically come and go
  • Location: Affects the colon and rectum continuously
  • Severity: Can range from mild to severe

Risk Factors

  • Age: Usually develops before 30
  • Family history
  • Ethnicity (more common in white people)
  • Environmental factors

Diagnosis

  • Colonoscopy
  • Blood tests
  • Stool samples
  • Imaging studies

Treatment Options

  1. Medications:

    • Anti-inflammatory drugs
    • Immunosuppressants
    • Biologics
    • Antibiotics
  2. Lifestyle Changes:

    • Dietary modifications
    • Stress management
    • Regular exercise
    • Smoking cessation
  3. Surgery (if necessary):

    • Removal of colon and rectum
    • J-pouch surgery

Living with UC

  • Regular medical check-ups
  • Maintaining medication schedule
  • Identifying trigger foods
  • Building a support network

When to Seek Medical Care

  • Severe abdominal pain
  • Heavy diarrhea
  • Significant bleeding
  • High fever
  • Severe dehydration

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