Understanding Skin Cancer Prevention Medications: A Patient's Guide

Essential Information About Medications Used to Prevent and Treat Pre-Cancerous Skin Conditions

Dermatology

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Last updated: Mar 24, 2025

Introduction

Medications play a crucial role in preventing skin cancer development, especially in high-risk patients. This guide covers the most common preventive medications and their proper use.

Topical Medications

5-Fluorouracil (5-FU)

  • Brand names: Efudex®, Carac®
  • Usage: Applied to pre-cancerous spots
  • Duration: Typically 2-4 weeks
  • Common effects: Redness, irritation, crusting

Imiquimod

  • Brand names: Aldara®, Zyclara®
  • Usage: Treats actinic keratoses and superficial basal cell carcinoma
  • Schedule: 2-3 times per week
  • Duration: 4-16 weeks depending on condition

Ingenol Mebutate

  • Brand name: Picato®
  • Usage: Short-course treatment for actinic keratoses
  • Duration: 2-3 days

Oral Medications

Nicotinamide (Vitamin B3)

  • Dosage: 500mg twice daily
  • Benefits: Reduces risk in high-risk patients
  • Best for: Patients with history of multiple skin cancers

Important Considerations

  1. Always use as directed by your dermatologist
  2. Complete full course of treatment
  3. Report severe reactions immediately
  4. Combine with sun protection measures

Follow-up Care

  • Regular skin checks
  • Sun protection compliance
  • Medication adjustments as needed

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