Understanding Sarcoidosis

A Comprehensive Guide to Diagnosis, Treatment, and Management

Internal Medicine

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Last updated: Mar 24, 2025

What is Sarcoidosis?

Sarcoidosis is a multi-system inflammatory disorder characterized by the formation of tiny clusters of inflammatory cells called granulomas in various organs throughout the body.

Key Facts

  • Most commonly affects the lungs and lymph nodes
  • Can occur at any age but typically develops between 20-40 years
  • More common in women and certain ethnic groups
  • Often discovered incidentally on chest X-rays

Common Symptoms

General Symptoms

  • Fatigue
  • Fever
  • Weight loss
  • Night sweats

Organ-Specific Symptoms

Pulmonary

  • Persistent dry cough
  • Shortness of breath
  • Chest pain

Skin

  • Rashes
  • Nodules
  • Erythema nodosum

Eyes

  • Blurred vision
  • Eye pain
  • Light sensitivity

Diagnosis

  1. Medical history and physical examination
  2. Chest X-ray
  3. Pulmonary function tests
  4. Tissue biopsy
  5. Blood tests

Treatment Options

Monitoring

  • Some cases resolve spontaneously
  • Regular monitoring may be sufficient for mild cases

Medications

  • Corticosteroids (primary treatment)
  • Immunosuppressants
  • Antimalarial medications

Living with Sarcoidosis

  • Regular medical check-ups
  • Healthy lifestyle maintenance
  • Stress management
  • Support group participation

When to Seek Medical Attention

  • Worsening breathing problems
  • New or worsening vision problems
  • Irregular heartbeat
  • Severe fatigue

Prognosis

Many patients have a good prognosis with appropriate treatment and monitoring. The condition can:

  • Resolve spontaneously
  • Become chronic but stable
  • Require ongoing management

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