Understanding Pompholyx (Dyshidrotic Eczema)

A Comprehensive Guide to Causes, Symptoms, and Treatment Options

Dermatology

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Last updated: Mar 24, 2025

What Is Pompholyx?

Pompholyx, also known as dyshidrotic eczema, is a chronic skin condition characterized by small, intensely itchy blisters that develop on the hands and feet.

Key Symptoms

  • Small, fluid-filled blisters (vesicles)
  • Intense itching and burning sensation
  • Redness and inflammation
  • Scaling and peeling skin
  • Deep-set blisters on palms and soles
  • Painful cracks in the skin

Common Triggers

  • Stress
  • Allergic reactions
  • Exposure to metals (especially nickel)
  • Hot and humid weather
  • Excessive hand washing
  • Contact with irritants

Diagnosis

Diagnosis is typically based on:

  • Physical examination
  • Medical history review
  • Patch testing (in some cases)
  • Skin biopsy (rarely needed)

Treatment Options

Immediate Relief

  • Cold compresses
  • Over-the-counter antihistamines
  • Moisturizing creams

Medical Treatments

  1. Topical Treatments

    • Corticosteroid creams
    • Tacrolimus or pimecrolimus
    • Moisturizing ointments
  2. Oral Medications

    • Oral steroids (severe cases)
    • Immunosuppressants
    • Anti-inflammatory drugs

Prevention Strategies

  • Avoid known triggers
  • Protect hands with gloves
  • Use gentle soaps
  • Keep skin moisturized
  • Manage stress levels
  • Avoid excessive hand washing

When to Seek Medical Help

Consult a healthcare provider if:

  • Blisters become painful
  • Signs of infection appear
  • Symptoms interfere with daily activities
  • Traditional treatments aren't effective

Long-term Management

  • Regular moisturizing routine
  • Trigger avoidance
  • Stress management
  • Regular medical follow-up

Complications

  • Secondary bacterial infections
  • Chronic skin thickening
  • Nail changes
  • Impact on quality of life

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