Understanding Osteoporosis

A Comprehensive Guide to Bone Health Management

Endocrinology

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Last updated: Mar 24, 2025

What is Osteoporosis?

Osteoporosis is a progressive bone disease characterized by decreased bone mass and density, leading to an increased risk of fractures. The condition makes bones more porous and fragile.

Risk Factors

Non-modifiable Risk Factors:

  • Advanced age
  • Female gender
  • Family history
  • Previous fractures
  • Menopause

Modifiable Risk Factors:

  • Smoking
  • Excessive alcohol consumption
  • Sedentary lifestyle
  • Poor nutrition
  • Low calcium intake
  • Vitamin D deficiency

Symptoms

  • Early Stages: Usually asymptomatic
  • Advanced Stages:
    • Height loss
    • Stooped posture
    • Back pain
    • Easily occurring fractures

Diagnosis

Primary Screening Tools:

  • DEXA (Dual-energy X-ray Absorptiometry) scan
  • FRAX® tool for fracture risk assessment

Treatment Options

Medications:

  1. Bisphosphonates
  2. Selective Estrogen Receptor Modulators (SERMs)
  3. Hormone Therapy
  4. Biologics

Lifestyle Modifications:

  • Regular weight-bearing exercise
  • Balanced diet rich in calcium
  • Adequate vitamin D intake
  • Fall prevention strategies

Prevention

Daily Recommendations:

  • Calcium: 1000-1200mg daily
  • Vitamin D: 800-1000 IU daily
  • Regular exercise
  • Smoking cessation

When to Seek Medical Attention

  • Unexplained fractures
  • Significant height loss
  • Severe back pain
  • Family history of osteoporosis

Long-term Management

  • Regular bone density screenings
  • Medication compliance
  • Fall prevention
  • Regular medical follow-up

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