Understanding Nasopharyngeal Cancer

A Comprehensive Guide for Patients

Oncology

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Last updated: Mar 24, 2025

What is Nasopharyngeal Cancer?

Nasopharyngeal cancer (NPC) is a type of cancer that develops in the nasopharynx, the upper part of the throat behind the nose where it connects with the nasal cavity.

Risk Factors

  • Geographic location: More common in Southeast Asia and North Africa
  • Genetic factors: Family history of NPC
  • Epstein-Barr virus (EBV) infection
  • Diet: Consumption of salt-preserved foods
  • Tobacco and alcohol use

Common Symptoms

  • Stuffy nose or bloody nasal discharge
  • Hearing problems or ringing in ears (tinnitus)
  • Headaches
  • Facial pain or numbness
  • Difficulty opening mouth
  • Blurred or double vision
  • Neck lumps (enlarged lymph nodes)

Diagnosis

Initial Assessment

  • Physical examination
  • Detailed medical history
  • Nasopharyngoscopy

Confirmatory Tests

  • Biopsy
  • MRI or CT scanning
  • PET scan for staging
  • EBV DNA testing

Treatment Options

  1. Radiation Therapy

    • Primary treatment for most cases
    • Often used with chemotherapy
  2. Chemotherapy

    • May be given before, during, or after radiation
    • Different drug combinations used
  3. Surgery

    • Limited role
    • Mainly for residual or recurrent disease

Follow-up Care

  • Regular check-ups
  • Imaging tests
  • EBV DNA monitoring
  • Management of treatment side effects

Prognosis

Prognosis depends on:

  • Cancer stage at diagnosis
  • Response to treatment
  • Overall health status
  • EBV DNA levels

Support and Resources

  • Support groups
  • Nutritional counseling
  • Rehabilitation services
  • Mental health support

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