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Understanding Multiple Sclerosis Treatment Options: A Comprehensive Guide

Modern Approaches to Managing MS Symptoms and Disease Progression

Neurology

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Last updated: Mar 24, 2025

Disease-Modifying Therapies (DMTs)

Injectable Medications

  • Beta interferons (Avonex®, Betaseron®, Rebif®)
  • Glatiramer acetate (Copaxone®)
  • Peginterferon beta-1a (Plegridy®)

Oral Medications

  • Fingolimod (Gilenya®)
  • Dimethyl fumarate (Tecfidera®)
  • Siponimod (Mayzent®)
  • Teriflunomide (Aubagio®)

Infusion Treatments

  • Ocrelizumab (Ocrevus®)
  • Natalizumab (Tysabri®)
  • Alemtuzumab (Lemtrada®)

Symptom Management

Mobility Issues

  • Physical therapy
  • Assistive devices
  • Dalfampridine (Ampyra®)

Spasticity

  • Baclofen
  • Tizanidine
  • Physical therapy exercises

Fatigue Management

  • Energy conservation techniques
  • Modafinil
  • Amantadine

Lifestyle Modifications

Exercise and Physical Activity

  • Supervised exercise programs
  • Aquatic therapy
  • Yoga and stretching

Diet and Nutrition

  • Balanced diet
  • Vitamin D supplementation
  • Adequate hydration

Treatment Selection Factors

  • Disease type (relapsing-remitting vs. progressive)
  • Severity of symptoms
  • Lifestyle considerations
  • Side effect profiles
  • Cost and insurance coverage

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