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Understanding Modern Migraine Treatment Options

A Comprehensive Guide to Managing Migraine Headaches

Neurology

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Last updated: Mar 24, 2025

Acute Treatments

Over-the-Counter Medications

NSAIDs: Ibuprofen, naproxen, aspirin
Acetaminophen: For pain relief
Combination medications: Containing caffeine

Prescription Medications

Triptans
- Sumatriptan
- Rizatriptan
- Available as pills, nasal sprays, or injections
CGRP Antagonists (Gepants)
- Ubrogepant
- Rimegepant
Anti-nausea medications

Preventive Treatments

Daily Medications

Beta-blockers
Calcium channel blockers
Antidepressants
Anticonvulsants

Injectable Treatments

CGRP monoclonal antibodies
- Monthly or quarterly injections
- Specifically designed for migraine prevention
Botulinum toxin (Botox)
- Every 12 weeks
- For chronic migraine

Lifestyle Modifications

Trigger Management

Stress reduction
Regular sleep schedule
Dietary modifications
Exercise routine

Non-Pharmaceutical Approaches

Acupuncture
Biofeedback
Cognitive behavioral therapy
Relaxation techniques

When to Seek Emergency Care

Sudden, severe headache
Neurological symptoms
Fever with headache
Vision changes

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