Understanding Melanoma: A Patient's Guide to Prevention and Treatment

Essential Information About Skin Cancer Medications and Management

Dermatology

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Last updated: Mar 24, 2025

Introduction

Melanoma is a serious form of skin cancer that requires careful attention and proper medical management. This guide will help you understand the medications and treatments available.

Common Medications for Melanoma Treatment

Targeted Therapy

  • BRAF Inhibitors

    • Vemurafenib (Zelboraf®)
    • Dabrafenib (Tafinlar®)
    • Used for melanomas with BRAF mutations
  • MEK Inhibitors

    • Trametinib (Mekinist®)
    • Cobimetinib (Cotellic®)
    • Often combined with BRAF inhibitors

Immunotherapy

  • Checkpoint Inhibitors
    • Pembrolizumab (Keytruda®)
    • Nivolumab (Opdivo®)
    • Ipilimumab (Yervoy®)

Side Effect Management

Common Side Effects

  1. Skin reactions
  2. Fatigue
  3. Gastrointestinal issues
  4. Joint pain

When to Contact Your Doctor

  • Severe rash or blistering
  • Fever above 101.5°F
  • Severe diarrhea
  • Unusual breathing difficulties

Prevention Strategies

  • Apply broad-spectrum sunscreen (SPF 30+)
  • Wear protective clothing
  • Avoid peak sun hours (10 AM - 4 PM)
  • Regular skin self-examinations

Follow-up Care

  • Maintain regular dermatology appointments
  • Document any new skin changes
  • Keep medication schedule as prescribed
  • Monitor and report side effects

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