Understanding Lyme Disease

A Comprehensive Guide to Diagnosis, Treatment, and Prevention

Family Medicine

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Last updated: Mar 24, 2025

What is Lyme Disease?

Lyme disease is a bacterial infection caused by Borrelia burgdorferi bacteria, transmitted through the bite of infected black-legged (deer) ticks.

Key Symptoms

Early Signs (3-30 days after tick bite):

  • Bull's-eye rash (erythema migrans)
  • Fever and chills
  • Fatigue
  • Muscle and joint aches
  • Headache
  • Swollen lymph nodes

Later Signs (days to months):

  • Severe joint pain and swelling
  • Neurological problems
  • Heart rhythm irregularities
  • Additional rashes

Diagnosis

Diagnosis typically involves:

  1. Medical history evaluation
  2. Physical examination
  3. Blood tests (typically two-step testing)
  4. Assessment of symptoms

Treatment

Early-Stage Treatment

  • Oral antibiotics (typically 14-21 days)
    • Doxycycline
    • Amoxicillin
    • Cefuroxime

Late-Stage Treatment

  • Intravenous antibiotics
  • Longer treatment duration
  • Symptom management

Prevention

  1. Avoid tick-infested areas
  2. Use insect repellent
  3. Wear protective clothing
  4. Check for ticks after outdoor activities
  5. Remove ticks promptly

Long-Term Outlook

Most patients recover fully with timely antibiotic treatment. Some may experience post-treatment Lyme disease syndrome (PTLDS).

When to Seek Medical Care

Contact your healthcare provider if you:

  • Notice a bull's-eye rash
  • Experience symptoms after a tick bite
  • Have been in tick-prone areas and develop symptoms

Risk Factors

  • Living in or visiting woodland areas
  • Outdoor activities in high-risk areas
  • Exposed skin in tick habitats
  • Spring and summer seasons

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