Understanding Liver Transplantation

A Comprehensive Guide for Patients and Families

General Surgery

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Last updated: Mar 24, 2025

What is a Liver Transplant?

A liver transplant is a surgical procedure that removes a diseased liver and replaces it with a healthy donor liver. It's typically considered when liver disease has progressed to end-stage liver failure.

When Is a Transplant Needed?

Common conditions requiring transplantation include:

  • Cirrhosis
  • Hepatitis B or C
  • Primary liver cancer
  • Alcoholic liver disease
  • Autoimmune liver diseases
  • Genetic liver disorders

The Transplant Process

1. Evaluation

  • Comprehensive medical assessment
  • Psychological evaluation
  • Financial and insurance review
  • Blood type and tissue matching

2. Waiting Period

  • Placement on national transplant waiting list
  • MELD score determination
  • Regular health monitoring

3. Surgery

Duration: 4-8 hours Types:

  • Deceased donor transplant
  • Living donor transplant (partial liver)

4. Recovery

  • Initial ICU stay (2-4 days)
  • Hospital stay (1-2 weeks)
  • Home recovery (3-6 months)

Post-Transplant Care

Medications

  • Immunosuppressants
  • Anti-infection medications
  • Other prescribed medications

Follow-up Care

  • Regular clinic visits
  • Blood tests
  • Lifestyle modifications

Success Rates and Outlook

  • 1-year survival rate: ~90%
  • 5-year survival rate: ~75%
  • Quality of life typically improves significantly

Potential Complications

  • Rejection
  • Infection
  • Bleeding
  • Bile duct complications

Living with a Transplanted Liver

  • Maintain a healthy lifestyle
  • Take medications as prescribed
  • Regular medical check-ups
  • Avoid alcohol
  • Practice good hygiene

Support Resources

  • Transplant team contact
  • Support groups
  • Mental health services
  • Financial counseling

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