Understanding Liver Cancer

A Comprehensive Guide for Patients and Caregivers

Oncology

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Last updated: Mar 24, 2025

What is Liver Cancer?

Liver cancer occurs when abnormal cells in the liver begin to multiply uncontrollably. The liver, an essential organ for detoxification and protein synthesis, can develop two main types of cancer:

  • Primary liver cancer: Originates in the liver
  • Secondary liver cancer: Spreads to the liver from elsewhere

Types of Liver Cancer

Primary Liver Cancer

  1. Hepatocellular Carcinoma (HCC)

    • Most common type (80-90% of cases)
    • Usually develops in cirrhotic livers
    • More common in men
  2. Cholangiocarcinoma

    • Develops in bile ducts
    • Less common but more aggressive

Risk Factors

  • Chronic hepatitis B or C infection
  • Cirrhosis
  • Heavy alcohol consumption
  • Nonalcoholic fatty liver disease
  • Diabetes
  • Obesity
  • Exposure to aflatoxins

Symptoms

  • Unexplained weight loss
  • Loss of appetite
  • Upper abdominal pain
  • Nausea and vomiting
  • General weakness and fatigue
  • Jaundice (yellowing of skin and eyes)
  • White, chalky stools

Diagnosis

Common Diagnostic Tools

  • Blood tests (AFP levels)
  • Imaging (ultrasound, CT, MRI)
  • Liver biopsy
  • Staging scans

Treatment Options

  1. Surgery

    • Partial hepatectomy
    • Liver transplantation
  2. Non-surgical Treatments

    • Ablation therapy
    • Embolization
    • Radiation therapy
    • Targeted therapy
    • Immunotherapy

Prevention

  • Get vaccinated against hepatitis B
  • Avoid excessive alcohol consumption
  • Maintain healthy weight
  • Regular medical check-ups
  • Practice safe sex
  • Don't share needles

Prognosis and Survival

Prognosis depends on:

  • Cancer stage at diagnosis
  • Liver function
  • Overall health status
  • Treatment response

Support and Resources

  • Join support groups
  • Seek counseling if needed
  • Maintain regular communication with healthcare team
  • Consider lifestyle modifications

When to Seek Medical Attention

Contact your healthcare provider if you experience:

  • Persistent abdominal pain
  • Unexpected weight loss
  • Yellowing of skin or eyes
  • Unusual fatigue

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