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Understanding Inflammatory Bowel Disease Treatment Options

A Comprehensive Guide to Managing IBD

Gastroenterology

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Last updated: Mar 24, 2025

Introduction

Inflammatory Bowel Disease (IBD) encompasses chronic inflammatory conditions affecting the digestive tract, primarily Crohn's Disease and Ulcerative Colitis. This guide explores available treatment options.

Medication Options

Anti-inflammatory Drugs

  • 5-Aminosalicylates (5-ASAs)
    • Mesalamine
    • Sulfasalazine
    • Best for mild to moderate cases

Immunomodulators

  • Traditional Options
    • Azathioprine
    • 6-mercaptopurine
    • Methotrexate

Biologics

  • Anti-TNF Agents
    • Infliximab
    • Adalimumab
  • Other Biologics
    • Vedolizumab
    • Ustekinumab

Dietary Management

  • Identify trigger foods
  • Work with registered dietitian
  • Consider specialized diets

Surgical Options

  • For Ulcerative Colitis
    • Total colectomy
    • J-pouch surgery
  • For Crohn's Disease
    • Bowel resection
    • Strictureplasty

Lifestyle Modifications

  1. Stress management
  2. Regular exercise
  3. Smoking cessation
  4. Adequate sleep

Regular Monitoring

  • Follow-up appointments
  • Laboratory tests
  • Colonoscopy as needed
  • Vaccination updates

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