Understanding Hypoparathyroidism

A Comprehensive Guide to Parathyroid Hormone Deficiency

Endocrinology

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Last updated: Mar 24, 2025

What is Hypoparathyroidism?

Hypoparathyroidism is a rare endocrine disorder characterized by abnormally low levels of parathyroid hormone (PTH) in the body. This condition affects the body's ability to regulate calcium and phosphorus levels.

Key Symptoms

  • Muscle cramps and spasms
  • Tingling in fingers, toes, and lips
  • Fatigue
  • Anxiety or depression
  • Dry, coarse skin
  • Brittle nails
  • Seizures (in severe cases)

Common Causes

  1. Post-surgical: Most common cause, following thyroid surgery
  2. Autoimmune disorders
  3. Genetic conditions
  4. Radiation therapy to the neck

Diagnosis

Diagnosis involves:

  • Blood calcium levels testing
  • PTH level measurement
  • Phosphorus level testing
  • Magnesium level assessment
  • Urine calcium testing

Treatment Options

Immediate Management

  • Calcium supplementation
  • Active vitamin D (calcitriol)
  • Regular monitoring of blood levels

Long-term Care

  • Daily medication compliance
  • Regular medical check-ups
  • Dietary modifications
  • Lifestyle adjustments

Complications

  • Calcium deposits in kidneys
  • Cataracts
  • Dental problems
  • Heart rhythm abnormalities

Living with Hypoparathyroidism

Diet Recommendations

  • Calcium-rich foods
  • Vitamin D-rich foods
  • Limited phosphorus intake

Lifestyle Modifications

  • Regular exercise
  • Stress management
  • Consistent medication schedule
  • Regular monitoring

When to Seek Medical Help

  • Severe muscle spasms
  • Seizures
  • Difficulty breathing
  • Persistent tingling sensations

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