Understanding Goitre

A Comprehensive Guide to Thyroid Enlargement

Endocrinology

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Last updated: Mar 24, 2025

What is a Goitre?

A goitre is an enlargement of the thyroid gland, which is located in the front of your neck. This butterfly-shaped gland normally sits just below your Adam's apple.

Common Causes

  • Iodine deficiency: Most common cause worldwide
  • Hashimoto's disease: An autoimmune condition
  • Graves' disease: Causes hyperthyroidism
  • Thyroid nodules: Single or multiple growths
  • Pregnancy: Hormonal changes can cause temporary enlargement

Symptoms

Physical Signs

  • Visible swelling in the neck
  • Feeling of tightness in the throat
  • Difficulty swallowing
  • Hoarseness
  • Coughing

Associated Symptoms

Depending on thyroid function:

  • Weight changes
  • Changes in energy levels
  • Hair and skin changes
  • Temperature sensitivity

Diagnosis

  1. Physical examination
  2. Blood tests (TSH, T3, T4)
  3. Ultrasound imaging
  4. Thyroid scan (if needed)
  5. Fine-needle aspiration biopsy

Treatment Options

Conservative Management

  • Iodine supplementation (if deficient)
  • Regular monitoring
  • Lifestyle modifications

Medical Treatment

  • Thyroid hormone replacement
  • Anti-thyroid medications
  • Radioactive iodine therapy

Surgical Options

  • Partial thyroidectomy
  • Total thyroidectomy

When to Seek Medical Attention

  • Rapid growth of neck swelling
  • Difficulty breathing or swallowing
  • Voice changes
  • Associated symptoms of thyroid dysfunction

Prevention

  • Adequate iodine intake
  • Regular medical check-ups
  • Awareness of family history
  • Avoiding radiation exposure

Long-term Management

  • Regular monitoring of thyroid function
  • Medication compliance if prescribed
  • Follow-up appointments
  • Lifestyle modifications as needed

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