Understanding Decongestants

A Patient's Guide to Safe and Effective Use

Family Medicine

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Last updated: Mar 24, 2025

What Are Decongestants?

Decongestants are medications that help relieve nasal congestion by reducing swelling and inflammation in the nasal passages and sinuses.

How Do They Work?

Decongestants work by:

  • Constricting blood vessels in the nasal passages
  • Reducing tissue swelling
  • Decreasing mucus production

Common Types

Oral Decongestants

  • Pseudoephedrine (Sudafed)
  • Phenylephrine (Sudafed PE)

Nasal Sprays

  • Oxymetazoline (Afrin)
  • Phenylephrine (Neo-Synephrine)

Important Safety Information

Precautions

  • Not recommended for children under 4 years
  • Use with caution if you have:
    • High blood pressure
    • Heart disease
    • Diabetes
    • Thyroid problems

Side Effects

  • Increased blood pressure
  • Nervousness
  • Insomnia
  • Rapid heartbeat

Usage Guidelines

  1. Follow recommended dosage
  2. Don't use nasal sprays for more than 3 days
  3. Take oral decongestants with food
  4. Stay hydrated

When to Seek Medical Advice

Consult your healthcare provider if:

  • Symptoms persist beyond 7 days
  • You experience severe side effects
  • You have underlying health conditions

Drug Interactions

Decongestants may interact with:

  • MAO inhibitors
  • Blood pressure medications
  • Some antidepressants

Alternative Options

  • Saline nasal sprays
  • Steam inhalation
  • Nasal strips
  • Humidifiers

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