Understanding Colorectal Cancer: A Comprehensive Overview

Essential Information for Patients and Families

Oncology

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Last updated: Mar 24, 2025

What Is Colorectal Cancer?

Colorectal cancer is a malignancy that begins in either the colon (large intestine) or rectum. It typically starts as small, benign growths called polyps that can become cancerous over time.

Key Statistics

  • Third most common cancer in the United States
  • Affects both men and women
  • Most cases occur after age 50

Risk Factors

  • Age: Risk increases after 50
  • Family History: Especially first-degree relatives
  • Lifestyle Factors:
    • Poor diet (high in red meat, low in fiber)
    • Lack of physical activity
    • Obesity
    • Smoking
    • Heavy alcohol use

Warning Signs

  1. Changes in bowel habits
  2. Rectal bleeding or blood in stool
  3. Persistent abdominal discomfort
  4. Unexplained weight loss
  5. Fatigue

Screening and Detection

  • Regular screening starting at age 45
  • Common Tests:
    • Colonoscopy (every 10 years)
    • FIT test (annually)
    • Stool DNA test (every 3 years)

Treatment Options

  • Surgery: Removal of tumor and affected tissue
  • Chemotherapy: Before or after surgery
  • Radiation: Often used for rectal cancer
  • Targeted Therapy: For specific genetic mutations

Prevention

  • Regular screenings
  • Healthy diet rich in fiber
  • Regular exercise
  • Maintaining healthy weight
  • Limiting alcohol
  • Not smoking

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