Understanding Cirrhosis of the Liver

A Comprehensive Guide for Patients

Gastroenterology

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Last updated: Mar 24, 2025

What is Cirrhosis?

Cirrhosis is a late-stage liver condition where healthy liver tissue is replaced by scar tissue (fibrosis), progressively impairing the liver's ability to function properly.

Common Causes

  • Chronic alcohol abuse
  • Viral hepatitis (B and C)
  • Nonalcoholic fatty liver disease (NAFLD)
  • Autoimmune hepatitis
  • Inherited disorders

Key Symptoms

Early Stage:

  • Fatigue
  • Weakness
  • Loss of appetite
  • Unexplained weight loss

Advanced Stage:

  • Yellowing of skin (jaundice)
  • Fluid accumulation in abdomen (ascites)
  • Easy bruising or bleeding
  • Confusion or difficulty thinking (hepatic encephalopathy)

Diagnosis

  • Physical examination
  • Blood tests
  • Imaging tests (ultrasound, CT, or MRI)
  • Liver biopsy

Treatment Options

Lifestyle Changes

  • Stopping alcohol consumption
  • Maintaining a healthy diet
  • Regular exercise when possible
  • Weight management

Medical Management

  • Medications for underlying causes
  • Treatment of complications
  • Regular monitoring
  • Vaccination against hepatitis

Advanced Care

  • Liver transplant evaluation when necessary
  • Management of portal hypertension
  • Treatment of varices

Prevention

  • Limit alcohol consumption
  • Practice safe sex
  • Avoid sharing needles
  • Maintain healthy weight
  • Get vaccinated against hepatitis

Living with Cirrhosis

  • Regular medical check-ups
  • Medication compliance
  • Avoiding certain medications
  • Following dietary restrictions
  • Monitoring for complications

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