Understanding Cholera

A Comprehensive Guide to Causes, Prevention, and Treatment

Gastroenterology

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Last updated: Mar 24, 2025

What is Cholera?

Cholera is an acute diarrheal illness caused by infection with the bacterium Vibrio cholerae. This infection affects the small intestine and can lead to severe dehydration if left untreated.

Key Symptoms

  • Severe watery diarrhea ('rice-water stools')
  • Vomiting
  • Muscle cramps
  • Rapid dehydration
  • Low blood pressure
  • Extreme thirst

Transmission

Cholera spreads primarily through:

  • Contaminated water
  • Contaminated food
  • Poor sanitation
  • Direct contact with infected feces

Risk Factors

  • Living in areas with poor sanitation
  • Limited access to clean water
  • Living in crowded conditions
  • Raw or undercooked seafood consumption

Prevention

  1. Water Safety

    • Drink only bottled or boiled water
    • Use safe water for brushing teeth
    • Avoid ice from unknown sources
  2. Food Safety

    • Eat thoroughly cooked foods
    • Avoid raw seafood
    • Choose fruits you can peel yourself
  3. Hygiene

    • Frequent handwashing
    • Proper disposal of waste
    • Clean food preparation surfaces

Treatment

Immediate Actions

  • Oral rehydration therapy (ORT)
  • IV fluids in severe cases
  • Antibiotics when necessary

Long-term Management

  • Maintaining hydration
  • Electrolyte balance
  • Proper nutrition

When to Seek Medical Care

Seek immediate medical attention if you experience:

  • Severe diarrhea
  • Rapid dehydration
  • Persistent vomiting

Prevention Through Vaccination

Vaccination is available and recommended for:

  • High-risk areas residents
  • Aid workers
  • Travelers to endemic regions

Complications if Untreated

  • Severe dehydration
  • Electrolyte imbalances
  • Kidney failure
  • Death within hours if untreated

Recovery and Follow-up

  • Maintain good hygiene
  • Complete prescribed medications
  • Follow dietary recommendations
  • Regular medical check-ups as advised

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