Understanding and Managing Ulcerative Colitis: A Comprehensive Patient Guide

Essential Information for Patients Living with UC

Gastroenterology

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Last updated: Mar 24, 2025

What is Ulcerative Colitis?

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the large intestine (colon) and rectum. It causes inflammation and ulcers in the digestive tract's innermost lining.

Common Symptoms

  • Diarrhea, often with blood or pus
  • Abdominal pain and cramping
  • Rectal pain and bleeding
  • Urgency to defecate
  • Weight loss
  • Fatigue
  • Fever

Diagnosis

Your gastroenterologist may use several methods to diagnose UC:

  • Colonoscopy
  • Blood tests
  • Stool samples
  • Imaging studies (X-rays, CT scans)

Treatment Options

Medications

  1. Anti-inflammatory drugs

    • 5-aminosalicylates (5-ASAs)
    • Corticosteroids
  2. Immunosuppressants

    • Azathioprine
    • Mercaptopurine
    • Cyclosporine
  3. Biologics

    • TNF-alpha inhibitors
    • Integrin inhibitors

Lifestyle Management

Diet Recommendations

  • Keep a food diary
  • Eat smaller, frequent meals
  • Stay hydrated
  • Avoid trigger foods
  • Consider working with a dietitian

Stress Management

  • Regular exercise
  • Adequate sleep
  • Relaxation techniques
  • Support groups

When to Contact Your Healthcare Provider

  • Severe abdominal pain
  • Heavy diarrhea
  • Significant bleeding
  • High fever
  • Severe fatigue

Long-term Outlook

While UC is a chronic condition, proper management can help achieve and maintain remission. Regular check-ups and medication compliance are essential.

Support Resources

  • Inflammatory Bowel Disease (IBD) support groups
  • Nutritional counseling
  • Mental health services
  • Patient advocacy organizations

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