Understanding and Managing Psoriasis: A Comprehensive Treatment Guide

Modern Therapeutic Options for Psoriasis Management

Dermatology

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Last updated: Mar 24, 2025

Introduction

Psoriasis is a chronic autoimmune condition that affects the skin, causing red, scaly patches. This guide explores available treatment options to help manage symptoms and improve quality of life.

Treatment Categories

1. Topical Treatments

  • Corticosteroids

    • First-line treatment for mild to moderate psoriasis
    • Various strengths available
    • Best for short-term use
  • Vitamin D Analogs

    • Calcipotriene and calcitriol
    • Help slow skin cell growth
    • Can be combined with steroids

2. Light Therapy (Phototherapy)

  • Narrowband UVB

    • Most common form
    • 2-3 sessions per week
    • Minimal side effects
  • PUVA

    • Combines UVA light with psoralen medication
    • More intensive treatment

3. Systemic Medications

  • Traditional Systemics

    • Methotrexate
    • Cyclosporine
    • Acitretin
  • Biologics

    • TNF-alpha inhibitors
    • IL-17 inhibitors
    • IL-23 inhibitors

Lifestyle Modifications

  • Maintain healthy weight
  • Avoid trigger foods
  • Manage stress
  • Keep skin moisturized

Treatment Selection Factors

  • Disease severity
  • Affected areas
  • Previous treatments
  • Comorbidities
  • Cost considerations

Regular Monitoring

  • Track symptom changes
  • Document side effects
  • Schedule follow-up appointments
  • Adjust treatment as needed

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