Understanding Acute Myeloid Leukemia (AML)

A Comprehensive Guide for Patients and Caregivers

Oncology

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Last updated: Mar 24, 2025

What is AML?

Acute Myeloid Leukemia is a type of blood and bone marrow cancer that affects the production of normal blood cells. It develops when abnormal white blood cells accumulate in the bone marrow, interfering with the production of healthy blood cells.

Key Symptoms

  • Fatigue and weakness
  • Frequent infections
  • Easy bruising or bleeding
  • Fever
  • Bone pain
  • Shortness of breath
  • Pale skin

Risk Factors

  • Age (more common in older adults)
  • Previous cancer treatment
  • Exposure to certain chemicals
  • Smoking
  • Certain blood disorders
  • Genetic conditions

Diagnosis

Primary Tests

  1. Complete Blood Count (CBC)
  2. Bone Marrow Biopsy
  3. Genetic Testing
  4. Flow Cytometry

Additional Assessments

  • Chest X-rays
  • Spinal Fluid Tests
  • Heart Function Tests

Treatment Options

Initial Treatment (Induction)

  • Chemotherapy
  • Targeted Therapy
  • Stem Cell Transplantation

Consolidation Treatment

  • Additional chemotherapy cycles
  • Maintenance therapy
  • Clinical trials

Prognosis

Prognosis varies depending on several factors:

  • Age
  • General health
  • Genetic features of the leukemia
  • Response to initial treatment

Living with AML

Self-Care Measures

  • Regular medical follow-up
  • Infection prevention
  • Proper nutrition
  • Physical activity as tolerated
  • Emotional support

Support Resources

  • Support groups
  • Patient organizations
  • Social workers
  • Mental health professionals

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