Guide to Colon Cancer Screening Medications and Preparations

Understanding Your Colonoscopy Prep Options

Gastroenterology

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Last updated: Mar 24, 2025

Overview

Proper bowel preparation is crucial for a successful colonoscopy. This guide explains the common medications and preparations you'll need to take.

Common Preparation Types

1. Polyethylene Glycol (PEG) Solutions

  • Examples: GoLYTELY®, NuLYTELY®, MoviPrep®
  • How to take: Mix with water
  • Volume: 4 liters typically
  • Timing: Split dose over evening before/morning of procedure

2. Low-Volume Solutions

  • Examples: SUPREP®, Clenpiq®
  • How to take: Mix with water (if required)
  • Volume: 2-3 liters total
  • Timing: Two doses, 10-12 hours apart

Important Guidelines

  1. Before Preparation:

    • Stop iron supplements 5 days before
    • Avoid high-fiber foods
    • Stay hydrated
  2. During Preparation:

    • Follow timing exactly
    • Drink all prescribed solution
    • Stay near bathroom

Side Effects and Management

  • Common Effects:

    • Nausea
    • Chills
    • Abdominal cramping
  • Management:

    • Drink slowly
    • Use straw
    • Stay cool
    • Follow dietary restrictions

When to Contact Doctor

  • Severe vomiting
  • Severe abdominal pain
  • Unable to finish preparation
  • Signs of dehydration

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