Esophageal Manometry: Complete Protocol Guide

Standard Operating Procedure for High-Resolution Manometry Testing

Gastroenterology

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Last updated: Mar 24, 2025

Pre-Procedure Requirements

Patient Preparation

  • NPO status for 6 hours prior to procedure
  • Discontinue medications affecting esophageal motility:
    • Smooth muscle relaxants (48 hours prior)
    • Prokinetics (72 hours prior)
    • PPI therapy (7 days prior if pH testing planned)

Equipment Setup

  • Calibrate manometry system
  • Verify catheter integrity
  • Prepare topical anesthetic
  • Ready pressure transducers

Procedure Steps

1. Initial Assessment

  • Verify patient identity and consent
  • Review relevant medical history
  • Document current symptoms
  • Explain procedure to patient

2. Catheter Placement

  1. Apply topical anesthetic to nostril
  2. Insert catheter through nostril at 30° angle
  3. Advance slowly with patient sips of water
  4. Position sensors across LES
  5. Verify placement via pressure topography

3. Recording Protocol

Baseline Measurements

  • Record 30-second basal pressure
  • Document respiratory pattern

Standard Test Protocol

  1. 10 wet swallows

    • 5mL water bolus
    • 30-second intervals
    • Patient supine position
  2. Multiple rapid swallows

    • 2mL water × 5 swallows
    • < 4 second intervals
  3. Solid swallows (if indicated)

    • Standard viscosity bolus
    • Document timing

Data Analysis

Key Measurements

  • Integrated relaxation pressure (IRP)
  • Distal contractile integral (DCI)
  • Distal latency (DL)
  • Break size

Classification

  • Apply Chicago Classification v4.0 criteria
  • Document any variants
  • Note technical limitations

Documentation Requirements

  • Complete procedure note
  • Technical parameters
  • Patient tolerance
  • Clinical impressions
  • Recommendations

Quality Metrics

  • Minimum 7/10 interpretable swallows
  • Proper catheter positioning
  • Adequate signal quality
  • Complete dataset acquisition

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