Depression Treatment: Recognizing Warning Signs and When to Seek Help

A Guide for Patients and Their Loved Ones

Psychiatry

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Last updated: Mar 24, 2025

Important Warning Signs During Depression Treatment

Worsening Symptoms

  • Increased feelings of hopelessness or worthlessness
  • Deepening sadness or emotional numbness
  • Growing difficulty with daily activities
  • Declining personal hygiene or self-care

Concerning Behavioral Changes

  • Withdrawal from treatment or medication non-compliance
  • Increased isolation from friends and family
  • Sudden mood swings or agitation
  • Changes in sleeping or eating patterns

Emergency Warning Signs

  • Suicidal thoughts or plans
  • Self-harm behaviors
  • Expressing feelings of being a burden
  • Giving away personal possessions

When to Contact Your Healthcare Provider

Immediate Action Required

  • Thoughts of self-harm or suicide
  • Severe side effects from medication
  • Sudden extreme mood changes

Schedule an Appointment When

  • Symptoms persist despite treatment
  • Side effects are bothersome
  • Medication doesn't seem effective
  • New symptoms develop

Support Resources

24/7 Emergency Contacts

  • National Suicide Prevention Lifeline: 988
  • Local Emergency Services: 911
  • Crisis Text Line: Text HOME to 741741

Treatment Support

  • Keep all scheduled appointments
  • Maintain communication with your healthcare team
  • Document symptoms and concerns
  • Involve trusted family members or friends

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