Bullous Pemphigoid: A Patient's Guide

What Is Bullous Pemphigoid?

Bullous pemphigoid (BP) is an autoimmune skin disorder that causes large, fluid-filled blisters (bullae) to develop on the skin. It primarily affects older adults and occurs when the immune system mistakenly attacks the skin's basement membrane.

Key Symptoms

• Large, fluid-filled blisters
• Severe itching (pruritus)
• Red, inflamed skin
• Patches that resemble hives
• Blisters typically appearing on:
  • Abdomen
  • Inner thighs
  • Arms and legs
  • Flexor surfaces

Risk Factors

• Age over 60 years
• Certain medications
• Autoimmune conditions
• UV radiation exposure
• Genetic predisposition

Diagnosis

Common Diagnostic Methods

1. Physical examination
2. Skin biopsy
3. Direct immunofluorescence
4. Blood tests for antibodies

Treatment Options

Medications

• Corticosteroids (topical and oral)
• Immunosuppressive drugs
• Anti-inflammatory medications

Supportive Care

• Wound care
• Skin protection
• Lifestyle modifications

Complications

• Secondary skin infections
• Fluid and electrolyte imbalances
• Side effects from medications

Living with Bullous Pemphigoid

Self-Care Tips

• Keep skin clean and protected
• Avoid skin trauma
• Follow medication schedules
• Regular medical follow-up
• Monitor for infection signs

When to Seek Medical Care

• New blisters appearing
• Signs of infection
• Worsening symptoms
• Medication side effects